Grant Name: Canadian Institute of Health Research

Status:

Active

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Deadline:

March 3, 2022

Description

Phase II of the Joint Canada-Israel Health Research Program (the Program) seeks to support fundamental research at the cutting-edge of biomedical science and global health. This first call for proposals under phase II is directed toward proposals at the intersection between non-communicable chronic disease (NCD) and infectious diseases while strengthening capacity in Canada, Israel and in low- and middle-income countries (LMIC).

The Program will support world-class research teams co-led by three principal investigators: one from Canada, one from Israel and one from an LMIC (see Appendix A for the list of eligible countries). The teams will integrate researchers from all three geographies with the intention of strengthening scientific capacity, promoting collaboration, equitable partnerships and scientific excellence in all its diversity. It is expected that the three principal investigators will work together on a cohesive research project with researchers from all three geographies contributing to and benefiting from their involvement in the project and the Program.

Both NCDs and infectious disease trajectories are highly influenced by genetic, biological, social, behavioural, and environmental factors across a person’s life cycle, which in turn impact gene expression, microbiome composition, and immune, metabolic and tissue functions. Pathogens that cause infectious diseases can directly and/or through inflammation processes exacerbate NCD progression and complications. Pre-existing NCDs can also modulate the host immune response to infection leading to severe corollaries and outcomes. While there is clearly a strong link between NCDs and infectious diseases, the full extent of the biological mechanisms underlying the intersection of NCDs, and infectious diseases remains to be fully understood. A system biology approach to better capture the larger picture of the complex interactions taking place across the intersecting molecular pathways can help gain a deeper understanding of potential new targets for prevention, diagnosis, and treatment that can promote equitable health outcomes for all (i.e., through consideration of sex, gender and other population characteristics).

Eligibility

For an application to be eligible:

  1. For administrative purposes only, the Nominated Principal Applicant must be the Canadian investigator co-leading the team.
  1. A maximum of one Principal Applicant must be the Israeli investigator co-leading the team.
  2. A maximum of one Principal Applicant must be the LMIC investigator co-leading the team.
  3. For the Canadian arm of the team, applications involving First Nations, Inuit, Métis and/or Urban Indigenous populations must include at least one participant who self-identifies as First Nations, Inuit, or Métis and/or who can demonstrate their experience of meaningful and culturally safe involvement with Indigenous Peoples in an Indigenous Health Research environment on the research team. At least one participant meeting this criteria must submit an “Other” attachment describing their experience working in an Indigenous Health Research environment.
    • If relevant, the LMIC investigator co-leading the team is invited to reflect on how their research application could involve Indigenous populations related to their specific context.
  1. In your knowledge mobilization plan, as a minimum eligibility requirement, all proposals must support at least one of the following activities aimed at supporting capacity and scientific relationships:
    • significant training opportunities such as scientific workshops, graduate training in low- and middle-income countries, Canada and Israel or summer schools benefiting researchers/trainees in eligible low and middle income countries; and/or

inclusion of trainees from low and middle income countries, Canada and Israel in carrying out the research.

How to Apply?

Note:

  • The application process for this funding opportunity is comprised of an ISF administrative application and a CIHR application, each consisting of a registration and application stage.
    • The Canadian, Israeli and LMIC investigators co-leading the team will submit one joint application through CIHR ResearchNet. In addition, the Israeli investigator is responsible for submitting a separate, administrative application to ISF.

ISF Application Process

  • The ISF administrative application process for this funding opportunity is comprised of two steps: Registration and Application.
  • In addition to submitting the application to CIHR, the Israeli investigator co-leading the team must register with the ISF online system, as described in the ISF specific guidelines.
  • Please refer to the Notices section for the deadline for the ISF administrative application.
  • ISF Budget:
    • The Israeli investigator will submit the final version of the “Budget details PDF” as was submitted in the administrative application to ISF. A copy of this must also be submitted in the CIHR ResearchNet application.

For further instructions regarding ISF requirements, see the ISF website.

CIHR Application Process

  • To complete your CIHR Registration, follow the instructions in the Grants – Registration Guidelines along with any additional instructions found below under “Specific Instructions”.
  • To complete your Joint Application to CIHR, follow the instructions in the Grants – Application Guidelines along with any additional instructions found below under “Specific Instructions”.
  • All participants listed, with the exception of Collaborators are required to:
  • The Canadian, Israeli and LMIC investigators co-leading the team are required to create CVs through the Canadian Common CV (CCV) website for their CIHR (ResearchNet) submissions. For information on how to create the required CIHR Registration CV and CIHR Biosketch CV, please visit CCV Frequently Asked Questions.
  • All other participants will be asked to submit an Applicant Profile CV. This is only necessary at the Application stage.

Specific Instructions to complete your CIHR ResearchNet application

Step 1 – Registration:

Task: Identify Participants

  • List all participants in the “Identify Participants” task. Consult the Eligibility section and ensure that all requirements are met. For administrative purposed, the Canadian investigator co-leading the team must be listed as the “Nominated Principal Applicant”.
  • The Israeli and LMIC investigators co-leading the team must be listed as “Principal Applicants”.
  • All other participants must be listed in the role of “Collaborator”, including the participant representing Indigenous Experience, if applicable.
  • The Canadian, Israeli and LMIC investigators co-leading the team are required to submit a CIHR Registration CV, using the Canadian Common CV (CCV) interface. Link each Registration CV to the application by entering the CCV confirmation number in the appropriate field for each applicant.
  • CVs for Collaborators are not required at this stage.

Task: Summary of Research Proposal

  • In a maximum of one page, describe how the proposal addresses the specific objectives and relevant research areas of the funding opportunity.

Task: Complete Peer Review Administration Information (Optional)

  • Suggest reviewers that have the expertise to review your application.

Task: Apply to Priority Announcements/Funding Pools

  • This is not required.

Step 2 – Application

Task: Identify Participants

  • List all participants in the “Identify Participants” task. Consult the Eligibility section and ensure that all requirements are met.
    • For administrative purposes, the Canadian investigator co-leading the team must be listed as the “Nominated Principal Applicant” (NPA).
    • The Israeli and LMIC investigators co-leading the team must be listed as “Principal Applicants” (PAs).
    • All other participants must be listed in the role of “Collaborator”, including the participant representing Indigenous Experience, if applicable.
  • The Canadian, Israeli and LMIC investigators co-leading the team are required to submit a CIHR Biosketch CV, using the Canadian Common CV (CCV) interface. Link each Biosketch CV to the application by entering the CCV confirmation number in the appropriate field for each applicant.
  • Provide a maximum of 10 CIHR Applicant Profile CVs for Collaborators based in Canada, Israel and the LMIC (maximum three pages per participant). If applicable, the participant representing Indigenous Experience must be included in the 10 Applicant Profile CV maximum.
    • Applicant Profile CVs must be uploaded separately in the task Attach Other Application Materials (see below).
  • All Collaborators must be listed in the Identify Participant task, as well as in the Participant Table (see “Task: Attach Other Application Materials” below); however, no CVs should be attached for these participants.

Task: Enter Proposal Information

  • Attach your Research Proposal. Note that the proposal must be organized using specific headers (see below).
  • In support of evidence demonstrating that documents written in French require approximately 20% more space than similar documents in English, applications written in French will be allowed two (2) additional pages for their research proposal. This provision will ensure an equitable amount of space for applications written in either official language. The following page limits for the research proposal will therefore apply:
    • Research proposals submitted in English – 10 pages
    • Research proposals submitted in French – 12 pages

Note: For research proposals submitted in English, any pages over the 10-page limit will be removed with no further notification to the Nominated Principal Applicant.

Research Proposal Headings

Organize your proposal using the following headings:

    • Objectives
      List the general and specific research, training, and networking objectives of your research project as they respond to this funding opportunity.
    • Scientific Background
      Provide an analysis of current research trends in this field and discuss the experience and achievements of the applicants.
    • Narrative Description
      Ensure that you consult the Evaluation Criteria and organize your description accordingly so that the criteria are addressed.
    • Ethical Considerations
      Present the ethical considerations inherent in the proposed research and explain plans to address them.
    • Time Schedule and Work Plan
      Detail anticipated key activities, milestones and deliverables for the research project (e.g., Gantt chart or other).
    • Collaboration Plan (1 page maximum)
      Applicants must include a Collaboration Plan for integrating researchers from the three arms of the project (i.e., Canada, Israeli and the LMIC) and establishing long-term scientific relationships between them. Describe how your proposal takes advantage of this funding opportunity to design a collaborative international research project. Detail your plan for integrating researchers in Canada, Israel and the LMIC, and identify the research and training activities that seek to support capacity and scientific relationships among the partners.

Task: Summary of Research Proposal

  • In a maximum of one page, describe how the proposal addresses the specific objectives and relevant research areas of the funding opportunity.

Task: Attach Other Application Materials

  • Upload the following documents as document type “Other”:
    • Knowledge Mobilization Plan (1 page maximum) – label as “Knowledge Mobilization Plan” (mandatory):
      • All proposals must support at least one of the following activities aimed at supporting capacity and scientific relationships:
        • significant training opportunities such as scientific workshops, graduate training in LMIC countries, Canada, and Israel or summer schools benefiting researchers/trainees in eligible LMIC; and/or
        • inclusion of trainees from LMIC, Canada, and Israel in carrying out the research.
    • Appendix (10 page maximum) – label as “Appendix”:
      • Attach the following as one document:
        • Up to 5 additional pages are permissible for figures and tables.
        • Up to 5 additional pages are permissible for references. References must be complete and titles should be written out in full.
    • Collaborator CVs – label each as “Collaborator CV – Name”:
      • Upload a maximum of ten (10) CIHR Applicant Profile CVs for Collaborators. See task Identify Participants (above) for details.
    • IDRC Budget – label each as “Proposal Budget and Timetable – Country” (mandatory):
    • Experience working in an Indigenous Health Research environment – label as “Indigenous Experience – Name” (if applicable):
      • For any Canadian research involving Indigenous Peoples, this funding opportunity seeks at least one participant who self-identify as Indigenous (First Nations, Inuit or Métis) and/or who can demonstrate their experience of meaningful and culturally safe  involvement with Indigenous Peoples in an Indigenous Health Research environment.
      • The participant(s) must submit a one (1) page attachment describing how they meet this requirement.”
    • ISF Budget (for Israeli Principal Applicants) – label as “ISF Budget” (mandatory):
      • Upload a copy of the “Budget details PDF”, as was submitted by the Israeli applicant co-leading the team (see ISF Administrative Application above).
      • The ISF budget must include all costs according to the ISF guidelines (see Appendix C).
      • The ISF budget must include all costs according to the ISF guidelines (see Appendix C) and abide by the ISF maximum per Israeli principal applicant (see Funds Available).
    • Sex- and Gender-Based Analysis (SGBA) and Equity, Diversity and Inclusion (EDI) (1 page maximum) – label as “SGBA and EDI” (mandatory):
      • Identify what biological (e.g. sex, age, etc.) and/or socio-cultural (e.g. gender, race, ethnicity, language) and/or identity factors and/or EDI are relevant to this research project and explain how they have been integrated into the proposed research design. If the team believes there are no relevant SGBA and/or EDI, provide a rationale for this.
  • Participant Table – upload as “Participant Table”:
    • In a table format, list all participants (including Collaborators) with their role on the application (co-lead, investigator, trainee, participant with Indigenous Experience [if applicable], partners, etc.), country, affiliation(s) and expertise.
    • All participants listed in this table must also be listed in the “Identify Participants” task, regardless of whether they are submitting a CV or not.
    • On this page, you must also indicate the ISF application number.

Task: Complete Peer Review Administration Information (optional)

  • Suggest reviewers you feel have the expertise to review your application. The funding agencies reserve the right to make the final selection of external reviewers. You should not suggest reviewers that have a conflict of interest.
  • Provide the names of individuals who you feel cannot provide an objective review of your application (reviewers to exclude), ensuring that you provide a reason for their exclusion.
  • The funding agencies reserve the right to make the final selection of reviewers.

Task: Print/ Upload Signature Pages

  • Required signatures:
    • The person authorized to sign research grants on behalf of the institution of the Canadian investigator co-leading the team (NPA) must provide their signature. In doing so, they certify that the research and budget proposal correctly and fairly reflect the financial plan of the proposed project, and more specifically the portion proposed for IDRC support. The signatories further certify that their institution will administer the grant as per IDRC’s terms and conditions.
    • Original signatures are not required. The scanned signed signature pages and the Routing Slip must be uploaded in the Print/Upload Signature Pages task in CIHR ResearchNet prior to submitting your application.

Task: Preview

  • Review all components of your application and ensure that every task is completed. If a task is incomplete, you must provide the missing information in order to successfully submit your application. To mark the preview task as complete, every other task must be marked as complete.

Task: Consent and Submit

  • Submit the completed electronic application to CIHR through ResearchNet by completing the “Consent and Submit” task.

By submitting your application, you are also consenting that your full application (including nominative information) will be shared with IDRC and ISF.

Funding Amount

Partner financial contributions for this initiative are subject to availability of funds. Should partner funding levels not be available or are decreased due to unforeseen circumstances, the partner(s) reserve(s) the right to reduce, defer, or suspend financial contributions to grants received as a result of this funding opportunity.

  • The total amount available for this funding opportunity is up to CAD 8,764,974, enough to fund up to six (6) grants. The maximum amount per grant is up to CAD 500,000 for the principal investigator from Canada, up to CAD 500,000 for the principal investigator from the LMIC and up to CAD 460,829 for the principal investigator from Israel over 4 years, for a total up to CAD 1,460,829 per team.
  • The following partners will administer the funded grants:
    • ISF will administer 6 funded grants to the institution of the Israeli applicant co-leading the team.
    • IDRC will administer 6 funded grants to the institution of the Canadian applicant co-leading the team.
    • IDRC will administer 6 funded grants to the institution of the LMIC applicant co-leading the team.

Contact Information

For all inquiries, please contact:

CIHR Contact Centre
Telephone: 613-954-1968
Toll Free: 1-888-603-4178
Email: support-soutien@cihr-irsc.gc.ca

For service hours, please consult our Contact us page.

Israeli applicants should direct their questions to ISF:

Ella Fire
Scientific Director Special Programs
Israel Science Foundation
Email: ella@isf.org.il

Processing Fee

N/A

Location/Classification

Canada
Research

English French
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